Soumya Raychaudhuri, M.D., Ph.D. (Member of the TAC; Brigham and Women’s Hospital / Broad Institute, Division of Rheumatology) has extensive experience in the investigation of immune-mediated diseases using genomics, genetics, and functional genomics. He has, with collaborators, led the mapping of common and rare disease alleles in rheumatoid arthritis and other complex diseases, as well as interpreting these data sets in the context of epigenetic data. He has used high throughput genotyping and next-generation sequencing to identify risk variants for complex diseases, including autoimmune diseases such as type 1 diabetes. With international collaborators, he has discovered >100 novel rheumatoid arthritis risk loci. More recently his group has used functional genomics data and single cell genomic data to identify likely causal cell-types and regulatory functions that risk alleles influence to confer disease risk.